Senior Bioinformatics Scientist Job at Integration International Inc., Lexington, MA

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  • Integration International Inc.
  • Lexington, MA

Job Description

Job Title: Bioinformatics Scientist/Computational Chemist/Biologist

Job Location: Lexington, MA

Pay Rate: $48/hr - $51/hr on W2

Top 3 Skills needed:

  • Patient endotype discovery using unsupervised/supervised ML approaches
  • Omics analysis (primarily proteomics, Olink, Soma, LC-MS) incl differential expression, clinical characterisation, clinical outcomes and pathway analyses
  • Experience with CDISC format (as my main work currently is on our RCT data)

Job Description:

We are seeking a highly motivated Senior Research Scientist to play a key role in supporting our Therapeutic Areas (TA) in their efforts to better characterise patients/diseases in a real-world context. Focussed initially on heart failure (HF), you will be responsible for (1) using patient-derived molecular and phenotypic data to identify treatment-relevant disease subgroups,

In this role you will:

  • Develop and apply advanced but explainable AI/ML methods and statistical models to cardiovascular disease
  • Collaborate with cross-functional teams across EVP areas to identify and validate new endotypes, biomarkers, and drug targets
  • Analyse large patient-derived molecular and phenotypic datasets, to identify patterns and trends that can inform future target discovery and development

Qualifications:

  • Master's degree in bioinformatics, Computational Biology, Computer Science / Machine Learning, Genomics, or related field (PhD candidates will be considered w/min of 1 yr prof exp)
  • 3+ years working/professional experience

Our ideal candidate meets the following criteria:

  • Has proven track record of delivering cohort analyses and clear interpretation of insights derived from machine learning
  • Has strong knowledge of machine learning algorithms and their application to biomedical data
  • Has experience with programming languages such as Python or R, version control, and high-performance computing.

We are looking for someone who thinks this sounds exciting and is motivated by keeping pace with developments in machine learning, real-world data, and cardiometabolic disease.

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